I have taken Tongkat Ali for some time but I am not sure about the results.
Right now I am taking Ashwagandha which is scientifically proven to lower cortisol and hence slightly increase testosterone
plus Rhodiola rosea (great adaptogen) and sometimes Eleuthero (Siberian ginseng, another adaptogen).
Those two are not directly linked to increasing testosterone but they can make you more resistant to stress and fatigue.
I was taking it for a while, 200mg/day, but didn’t see any improvements. My issue was too-high SHBG though, not just low T, so that probably played into it.
I stopped it cold turkey one day and didn’t see any negative effects, but that’s of course far too small of a data set (N=1) to draw any conclusions from.
It depends entirely on the other hormone levels; IMHO none of this is a “one-size-fits-all” approach, so every person needs to approach it based on their own biochemistry. As for who would take that much… I’ve seen people take amounts of stuff that I thought were crazy, and I’ve had those same people think I’m crazy for stuff that felt fine for me… The craziest biohacker I ever knew thought I was nuts for taking 10mg of melatonin at night… so… ?
I’m not a biochemist, so I won’t even attempt to go into an explanation of why they are not steroids, but the one I have used (Ostarine) has a very long safety record, and TBH I still have my gains from it, even after being off it since last summer. Thankfully the only banning of SARMs et al here have been for professional athletes, and since I don’t give a rat’s tiny little behind about sports at all… that doesn’t affect me. heh.
For the record though, I am looking at peptides as a lower-risk approach now, rather than SARMs. No matter what though, it’s my responsibility to do my homework about what’s safe to put in my body.
It didn’t seem to do that for me, I only took it for a month or so though, maybe it needs longer to work?
I need to get a new hormones panel done soon anyway as it’s been a long time, so I’ll see where I am. I’ve still got some tongkat ali left, maybe I’ll finish out the bottle.
Yes. With ashwagandha, it seemed like other adaptogens such as rhodiola and Siberian gensing. Just gentle, almost unnoticeable mellow-ness.
With KSM-66, I took it and WHOA! I felt very mellow. That WHOA effect lasted only a few weeks.
There are other extracts of ashwagandha now available, but I don’t know much about them other than I think they try to extract different compounds in them to have different effects.
I’m no expert in this domain, I’m just a guy who reads a lot and knows how to corroborate data to satisfy his own risk tolerance. I’m actually highly risk-averse, doubly so since I became a father.
Absolutely! As long as everyone remembers I’m just some (anonymous) guy on the internet lol.
As an example… a popular fat loss drug at the moment is semaglutide. In addition to the high cost and limited availability, I’m steering clear of this one for 2 reasons.
Semaglutide mimics the action of a hormone called glucagon-like peptide-1 (GLP-1) which binds to GLP-1 receptors in the body, which stimulates insulin secretion in response to elevated blood sugar levels. It also helps to suppress the release of glucagon, a hormone that raises blood sugar levels, and slows down the rate at which food is emptied from the stomach.
The problem here is that elevated insulin promotes fat storage, and the main mechanism for fat loss seems to be the appetite suppression. That would suggest that after going off the drug, the weight would return… and this does seem to be what studies show:
https ://diabetes.medicinematters.com/semaglutide/obesity/bodyweight-rebounds-after-semaglutide-withdrawal/20384552 (for some reason this site isn’t letting me link directly to the article)
The 2nd reason is that insulin is a primary driver of cancer growth…
Increasing my insulin levels is not something I want to do, ever. It’s shortsighted and foolish.
So yep. no semaglutide or tirzepatide for me. I also don’t like injections, but… that’s a minor point.