I had to decrease the exposure to 5 loops a week for my 3 sub stack due to the intensity of WB, KBC abd LD. Now it’s only one loop of LD a week. This one is a monster and I doubt anyone should run it more than once a week unless one is focused solely on healing and overcoming their limitations.
Genesis is a powerful sub as well and I wouldn’t run it more than twice a week myself.
Some subs like Genesis gave me what I wanted in 2-3 weeks, some, like DR needed more time. There are no fixed time frames, really.