Would cut down on the number of modules, most noticeably 1-2 Synergy, Omnidimensional or DEUS, and the APS modules.
The APS modules as they are straight up physical shifting for health (although they CAN work for WANTED style physical shifting with enough conscious guidance) which will put more strain due to differing aspects. Not impossible to run, but if we’re talking optimization for the sake of romantic pursuits, then cutting down the number would help.
Wouldn’t worry too much about Limiting People Remover removing potential help. Be aware it’s more for those toxic influences within your life, rather than on the spot “removal”. With conscious guidance, you could try having such an effect, but I haven’t seen reports on someone doing that yet.
If you’re listening to just your custom, then yes, you can leave Mosaic out. It will help the different modules work better with each other within a custom of course, but it’s more for stacking separate titles. Consider carefully if you are planning to stack.
Overall, you could run it as is but you would have to run it solo, and it would take a big longer as it’s maxed out to 20 with plenty of Synergy modules and physical shifting included (especially both health/attraction physical shifting, so conscious guidance is needed). Other option is cut it down, have faster results, be able to stack better.
Finally, be careful not to overload. You have aura + physical shifting at once. Can be energy taxing.