Wanted + LoTS is probably overkill, so, no need to have both in a stack at the same time.
Wanted kind of has a bit of a reputation for being “lazy” and somewhat diminishing maximum productivity, so it may be better to keep it out of a custom and listen to the standard program so that you can still listen to your non-wanted custom when you want all of the other goodness in the custom, but also need high productivity
Then the other option would be, well, what about Khan + EOG in a custom… but that’s two multi-stagers, so i wouldn’t do that.
Then the other other option would be, well, what about EOG1+Wanted… which runs in to the same problems relating to productivity.
So really, Khan shouldn’t be in a custom because you’ll need to transition through all four stages, wanted shouldn’t be in a custom because of productivity, LoTs shouldn’t be stacked with Wanted, EOG shouldn’t be in a custom because you’ll need to transition through multiple stages,
And sanguine doesn’t take a spot in your stack, so you can consider yourself allowed to have a 4-title stack so long as one of those titles is sanguine.
Sanguine elixir does take a spot in the stack tho, just to be clear.
Also, I would probably avoid running EOG + Khan, two multi stagers, together at all.
The PERFECT solution to this would be if Emperor had good enough effects on your feelings of masculinity that it would justify replacing Wanted out with Emperor.