Recently @James made a very insightful post, with this excerpt:
This reminded me of the self-help journey. I have all the conscious information to shift my mindset, but it’s not as seamless as when I was younger and full of optimism and faith. Any ideas?
Genesis and the Dragon line.
Then Khan Black, Hero: Origins, and the Revelation series.
Then, everything else. (It’s all ZP after all.)
A pillar of virtue
Yes according to @James , a pillar of virtue(s).
Virtues are important because they are the basic qualities necessary for our well being and happiness. By recognizing the importance of virtues, in our lives, it will lead to better communication, understanding and acceptance between us and our fellow man.
I remember this line but can’t remember who wrote it, “I do not seek to understand in order to believe, but I believe first in order to understand it.”
Because when we believe, it doesn’t matter how old we are, how much load we carry, with faith it will make us much stronger.
With LBFH alone will help you on this.
You’ll become attracted to things that will benefit you.
The loving one’s self comes first.
Love Bomb is better than LBFH for self love. This has been confirmed by both Saint and Fire.
Agreed on virtue tho, so I think a Hero Origins + Love Bomb stack would be INSANE
As for answering the original question of returning to a youthful neuroplasticity for change/development… maybe Quantum Limitless stacked with a title related to what you want to develop in yourself
I would say Genesis，I briefly used it for two cycles last years…it really boosted my confidence in the area I would love to advance …overall，it is a really fundamental sub that tackle a lot of things…it creates a good base for every thing to flourish…
also，dragon reborn：limit destroyer is a great sub for breaking mental barriers…I used it three cycles last years…and those strong masculine traits that I tapped in still stay with me now…it just helps you have this self efficient feeling…
if I have to add one more sub…then it will be Love Bomb….self love is a really soothing feeling…it just comforts you like a ideal motherly figure…it lifts you up when you need it…I am currently running it…I just feel at ease and loosened…
this is the stack I would recommend…. 
Dragon Reborn: Limit Destroyer, Genesis, Love Bomb comes to mind.
Depending on what you mean by opening your mind maybe also The Revelation of Mind.
As I understand your question, I’d recommend RoM as well.
Elixir could eliminate the self depriving and limiting thoughts and replace them with more positive ones. It could be a good addition for few cycles.
Revelation of Mind and it’s not even close. The “strengthen the link between your conscious and subconscious mind” scripting sounds like what you’re looking for. On top of that, it has elements of Minds Eye, and RAIKOV, which increase manifestation ability and your ability to “model” others who have the traits/attributes you’er looking for. I’ve ran just about every sub here, trust me this is the one your looking for. For me, it’s often the difference between seeing results with the other titles in my stack, and not seeing results. It’s really the ultimate supercharger.
However I’d also consider Limitless when the new update drops. I’ve asked support about this exact thing before. The cognitive enhancement titles like Limitless and QL, and the spiritual titles like the revelation series, and alchemist all contain that scripting, but ROM has seemed to really work the best for integrating conscious knowledge into the unconscious. It’s almost like you are aware of what the script is and what effects it’s having, and what results are coming from what title, which in my experience creates this massive feedback loop which tends to make the sub feel more like “it’s working”.
Can’t go wrong with Phoenix and Love Bomb… in my opinion that is. If nothing else run LB for a couple of cycles and go from there