Don’t start with 5 minutes, start with 30 seconds.
Haven’t seen complaints on this. Remember, running Paragon (or any title) doesn’t immunize you from things that just happen in life. Sometimes a headache is just that, a headache. Still, start off slow with 30 seconds.
It’s common for people to start feeling better, then immediately make themselves worse by pushing ahead and overusing the fact they feel better. Once you feel better, even though it’s tempting to immediately start doing things - rest. It needs time to integrate. And this isn’t strictly related to subs either.